15(R)-15-methyl Prostaglandin F2α
货号：
16730-10mg 基本售价：
5712.0 元 规格：
10 mg
产品信息
概述| 货号 | 16730-10mg |
| 描述 | 15(R)-15-methyl PGF2α is a metabolically stable analog of PGF2α. 15(R)-15-methyl PGF2α is an inactive, prodrug PGF agonist designed for activation by gastric acid after oral administration. Acid-catalyzed epimerization of 15(R)-15-methyl PGF2α converts it into the active 15(S)-isomer.1,2 The 15(S)-isomer induces luteolysis when injected in rhesus monkeys at a dose of about 12 mg/animal, while the 15(R)-isomer does not.3 |
| 别名 | 15(R)-15-methyl PGF2α; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Plaisted, S.M.,DeZwaan, J. and Snider, B.G. High-performance liquid chromatographic determination of acid-catalyzed degradation products of methyl carboprost in a polymeric controlled-release device. Journal of Chromatography 314, 369-377 (1984).
2.Hamberg, M.,Zhang, L.Y. and Bergström, S. On the pH-dependent degradation of 15(S)-15 methyl-prostaglandin F2α (carboprost). European Journal of Pharmaceutical Sciences 3, 27-38 (1995).
3.Wilks, J.W. Inhibition of the monkey corpus luteum with 15-methyl prostaglandins. Prostaglandins 20, 793-805 (1980).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 368.5 |
| 分子式 | C21H36O5 |
| CAS号 | 35864-81-4 |
| 稳定性 | ≥ 1 year |
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