| 货号 | 13650-10mg |
| 描述 | 13,14-dihydro-15-keto Prostaglandin E1(PGE1) is a metabolite of PGE1 with much reduced biological activity.1,2,3 Steady state plasma concentrations are about 10 pg/ml.1 13,14-dihydro-15-keto PGE1 is a weak inhibitor of ADP-induced platelet aggregation in human PRP and washed platelets with IC50 values of 54 and 200 µM, respectively, compared to PGE1 which has an IC50 of 40 nM.4 |
| 别名 | 13,14-dihydro-15-keto PGE1; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Leonhardt, A.,Krauss, M.,Gieler, U., et al. In vivo formation of prostaglandin E1 and prostaglandin E2 in atopic dermatitis. British Journal of Dermatology 136, 337-340 (1997). 2.Hamberg, M. and Samuelsson, B. On the metabolism of prostaglandins E1 and E2 in man. The Journal of Biological Chemisty 246, 6713-6721 (1971). 3.Peskar, B.A.,Cawello, W.,Rogatti, W., et al. On the metabolism of prostaglandin E1 administered intravenously to human volunteers. Journal of Physiology and Pharmacology 42, 327-331 (1991). 4.Kobzar, G.,Mardla, V.,Järving, I., et al. Antiaggregating potency of E-type prostaglandins in human and rabbit platelets. Proceedings of the Estonian Academy of Sciences.Chemistry 40, 179-180 (1991). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 354.5 |
| 分子式 | C20H34O5 |
| CAS号 | 5094-14-4 |
| 稳定性 | ≥ 1 year |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |