| 货号 | 13050-10mg |
| 描述 | Prostaglandin E1(PGE1) is not a major naturally occurring PG, but is widely administered clinically for several indications including peripheral occlusive vascular disease, erectile dysfunction, and in neonatal cardiology.1,2 COX metabolism of the unusual fatty acid 10,13,16-docosatrienoic acid yields 1a,1b-dihomo PGE1. This rare metabolite has been recovered from incubations of whole sheep seminal vesicles, but has not been reported in humans.3Inex vivo preparations of rat aorta and rat PRP, 1a,1b-dihomo PGE1 was found to be much less active than PGE1itself.4 |
| 别名 | 1a,1b-dihomo PGE1; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Virag, R.,Shoukry, K.,Floresco, J., et al. Intracavernous self-injection of vasoactive drugs in the treatment of impotence: 8-Year experience with 615 cases. Journal of Urology 145, 287-293 (1991). 2.Hoshi, K. Approved indications of lipo-PGE1 in Japan. Advanced Drug Delivery Reviews 20, 171-176 (1996). 3.Samel, N. and Maxey, K.M. Personal Communication. (2003). 4.Kloeze, J. Relationship between chemical structure and platelet-aggregation activity of prostaglandins. Biochimica et Biophysica Acta 187, 285-292 (1969). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 382.5 |
| 分子式 | C22H38O5 |
| CAS号 | 23452-98-4 |
| 稳定性 | ≥ 1 year |
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