E6 Berbamine
货号：
19358-50mg 基本售价：
5656.0 元 规格：
50 mg
产品信息
概述| 货号 | 19358-50mg |
| 描述 | E6 Berbamine is a calmodulin inhibitor that disrupts the activity of calmodulin-dependent enzymes such as myosin light chain kinase (IC50 = 8 µM) and phosphodiesterase 1A (IC50 = 0.53 µM).1 It is also reported to inhibit P-glycoprotein activity in purified primary cultured rat brain microvessel endothelial cells at 10 µM.2 |
| 别名 | Berbaminep-nitrobenzoate;O-(4-Nitrobenzoyl)berbamine; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Hu, Z.Y.,Gong, Y.S., and Huang, W.L. Interaction of berbamine compound E6 and calmodulin-dependent myosin light chain kinase. Biochemical Pharmacology 44(8), 1543-1547 (1992).
2.Zhu, H.J., and Liu, G.Q. Effect of E6, a novel calmodulin inhibitor, on activity of P-glycoprotein in purified primary cultured rat brain microvessel endothelial cells. Acta Pharmacologica Sinica 24(11), 1143-1149 (2003).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 757.8 |
| 分子式 | C44H43N3O9 |
| CAS号 | 114784-59-7 |
| 稳定性 | ≥ 1 year |
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