TIRAP (TLR2 and TLR4) Inhibitor Peptide Set
货号：
NBP2-29331 基本售价：
5641.3 元 规格：
2 mg
产品信息
概述| 货号 | NBP2-29331 |
| 反应种属 | Hu, MuSpecies Glossary |
| 目标/特异性 | The TIRAP inhibitory peptide contains a protein transduction (PTD) sequence (DRQIKIWFQNRRMKWKK) derived from antennapedia which renders the peptide cell permeable.
The control peptide consists of only the PTD sequence. |
性能| 供应商 | Novus |
| 免疫原 | Functions as a TIRAP decoy by binding to TIR interacting domains on specific TLR receptors. |
| 背景 | TIRAP/Mal is an adapter protein in the signaling pathways activated by TLR2 and TLR4, and appears to be essential for MyD88-dependent TLR2 and TLR4 signaling pathways. TIRAP is recruited to activated TL2 and TLR4 through interaction with TIR domain of the receptor. This peptide contains a sequence from mouse TIRAP that blocks the function of TIRAP, likely through binding to the receptor and blocking TIR-TIR domain interaction between TIRAP and the receptor. |
| 存放说明 | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| 存储溶液 | Solubilize the peptides prior to use by making 5 mM PBS* stock solutions (please see Preparation of 5 mM Stock Solutions under Preparation Method). |
| 浓度 | Lyoph |
