MyD88 Inhibitor Peptide Set
货号：
NBP2-29328 基本售价：
5641.3 元 规格：
2 mg
产品信息
概述| 货号 | NBP2-29328 |
| 反应种属 | Hu, Mu, Rt, Xp, ZeSpecies Glossary |
| 应用 | B/N, ELISA, Func-Inh, In vitro, In vivo |
性能| 供应商 | Novus |
| 免疫原 | Functions as a decoy by binding to the MyD88 TIR domain. |
| 背景 | MyD88 is an adapter protein that links Toll-like receptors (TLRs) and Interleukin-1 receptors (IL-1rs) with downstream signaling molecules. Homodimerization of MyD88 is a critical step in the signaling process, and allows the recruitment and activation of the kinase IRAK. MyD88 exists as a homodimer when recruited to activated TLR/IL-1Rs. The inhibitor peptide contains a sequence from the MyD88 TIR homodimerization domain (Loiarro, et al.). 1 MyD88 monomer binds to this inhibitor peptide, there by blocking MyD88 homodimerization. |
| 存放说明 | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| 存储溶液 | Solubilize the peptides prior to use by making 5 mM PBS* stock solutions (please see Preparation of 5 mM Stock Solutions under Preparation Method). |
| 浓度 | Lyoph |
