PtdIns-(1,2-dihexanoyl) (sodium salt)
货号：
9000660-1mg 基本售价：
5600.0 元 规格：
1 mg
产品信息
概述| 货号 | 9000660-1mg |
| 描述 | The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.1,2 PtdIns-(1,2-dihexanoyl) is a synthetic analog of natural PtdIns featuring C6:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol (DAG) stereochemistry as that of the natural compound. PtdIns are phosphorylated to mono- (PtdIns-P; PIP), di- (PtdIns-P2; PIP2), and triphosphates (PtdIns-P3; PIP3). Hydrolysis of PtdIns-(4,5)-P2 by phosphoinositide (PI)-specific phospholipase C generates IP3 and DAG which are key second messengers in an intricate biochemical signal transduction cascade. |
性能| 供应商 | Cayman |
| 应用文献 |
1.Exton, J.H. Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins. Annual Reviews of Pharmacology and Toxicology 36, 481-509 (1996).
2.Majerus, P.W. Inositol phosphate biochemistry. Annual Reviews of Biochemistry 61, 225-250 (1992).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 552.5 |
| 分子式 | C21H38O13P • Na |
| 稳定性 | ≥ 1 year |
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