EP2 Receptor (human) Reporter Assay Kit
货号:
601380-96Well 基本售价:
5600.0 元 规格:
96 wells
产品信息
概述货号 | 601380-96Well |
描述 | Prostaglandin E2(PGE2) is one of the most important biologically active prostanoids which exerts its actions mainly by binding to four distinct E-type prostanoid receptors: EP1, EP2, EP3, and EP4. These four G protein-coupled receptors (GPCRs) exhibit differences in signal transduction mechanisms, tissue localization, and regulation of expression. EP2 receptors are expressed in many tissues and cells to mediate various PGE2 actions. The receptors couple to Gs to stimulate the cAMP second messenger signal transduction pathway. EP2 receptors play important roles in mucosal protection, gastrointestinal secretion, and motility. The diverse effects of PGE2actingviaEP2 receptors make it an interesting drug target. Therefore, EP2 subtype selective agonists, antagonists, and modulators have been identified with potential therapeutic applications. |
别名 | PGE2 Receptor 2;Prostaglandin E2 Receptor 2; |
性能供应商 | Cayman |
运输条件 | Wet ice in continental US; may vary elsewhere |
存放说明 | -20 |
稳定性 | ≥ 1 year |
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