| 货号 | 11634-1g |
| 描述 | Natamycin is a naturally-occurring macrolide polyene antifungal agent produced during fermentation by the bacterium S. natalensis, commonly found in soil. With minimal inhibitory concentrations ranging from 4-64 μM, natamycin is used to treat fungal infections, including Candida,Aspergillus,Cephalosporium,Fusarium, and Penicillium.1,2,3 Natamycin blocks fungal growth by binding specifically to ergosterol with an apparent affinity of ~100 μM, but it does not permeabilize cell membranes as other polyene antibiotics are known to do.2 Natamycin is also used in the food industry as a "natural" preservative.4 |
| 别名 | Antibiotic A 5283;CL 12,625;Delvocid;E 235;Mycophyt;Myprozine;Pimaricin;Synogil;Tennecetin; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Lalitha, P.,Vijaykumar, R.,Prajna, N.V., et al. In vitro natamycin susceptibility of ocular isolates of Fusarium and Aspergillus species: Comparison of commercially formulated natamycin eye drops to pharmaceutical-grade powder. Journal of Clinical Microbiology 46(10), 3477-3478 (2008). 2.te Welscher, Y.M.,ten Napel, H.H.,Balagué, M.M., et al. Natamycin blocks fungal growth by binding specifically to ergosterol without permeabilizing the membrane. The Journal of Biological Chemisty 283(10), 6393-6401 (2008). 3.Dong, X.H.,Gao, W.J., and He, X.P. Antifungal efficacy of natamycin in experimental fusarium solani keratitis. Int.J.Ophthalmol. 5(2), 143-146 (2012). 4.de Vries, R.P.,de Lange, E.S.,Wösten, H.A.B., et al. Control and possible applications of a novel carrot-spoilage basidiomycete, Fibulorhizoctonia psychrophila. Antonie Van Leeuwenhoek 93, 407-413 (2008). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 665.7 |
| 分子式 | C33H47NO13 |
| CAS号 | 7681-93-8 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |