YZ9 (50 MG)
货号：
5048/50 基本售价：
5581.8 元 规格：
50 mg
产品信息
概述| 货号 | 5048/50 |
| 别名 | Ethyl 7-hydroxy-2-oxo-2H-1-benzopyran-3-carboxylate |
性能| 供应商 | Tocris |
| 生物活性 | PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) inhibitor (IC50 = 0.183 μM). Also competitively inhibits F-6-P (Ki = 0.094 μM). Inhibits cell growth (GI50 = 2.7 μM) in a XTT-based in vitro toxicology assay. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 234.2 |
| 分子式 | C12H10O5 |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO and to 20 mM in ethanol |
| 参考文献 | Seoet al (2011) Structure-based development of small molecule PFKFB3 inhibitors: a framework for potential cancer therapeutic agents targeting the Warburg effect. PLoS One 6 e24179. PMID: 21957443. |
