| 货号 | 1558/50 |
| 别名 | 4-(Butylamino)-1-ethyl-6-methyl 1H-pyrazolo[3,4b]pyridine-5-ethylca |
| 供应商 | Tocris |
| 生物活性 | Subtype-selective GABAA receptor modulator. Can potentiate or inhibit recombinant GABAA function depending on subunit combination. Enhances native GABAA receptor function and is anxiolytic following systemic administration in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 340.85 |
| 分子式 | C16H24N4O2.HCl |
| 可溶性/溶解性 | Soluble to 100 mM in 1eq. HCl |
| CAS号 | 41094-88-6 |
| 参考文献 | Thompsonet al (2002) Tracazolate reveals a novel type of allosteric interaction with recombinant γ-aminobutyric acidA receptors. Mol.Pharmacol. 61 861. PMID: 11901225. Meiners and Salama (1982) Enhancement of benzodiazepine and GABA binding by the novel anxiolytic, tracazolate. Eur.J.Pharmacol. 78 315. PMID: 6121710. Patel and Malick (1982) Pharmacological properties of tracazolate: a new non-benzodiazepine anxiolytic agent. Eur.J.Pharmacol. 78 323. PMID: 6121711. |