| 货号 | 5136/50 |
| 别名 | N,N-Dimethyl-5-(1H-1,2,4-triazol-1- |
| 供应商 | Tocris |
| 生物活性 | 5-HT1B/1D agonist. Antimigraine agent; attenuates effects of CGRP on light aversion in mice. Orally bioavailable. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 391.47 |
| 分子式 | C15H19N5.C7< |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 50 mM in DMSO |
| 参考文献 | Kaiseret al (2012) Modulation of CGRP-induced light aversion in wild-type mice by a 5-HT1B/D agonist. J.Neurosci. 32 15439. PMID: 23115181. Streetet al (1995) Synthesis and serotonergic activity of N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine and analogues: potent agonists for 5-HT1D receptors. J.Med.Chem. 38 1799. PMID: 7752204. |