| 货号 | 1029/25 |
| 别名 | [1α,4(S),6β,14α,16β]-20-Ethyl-1,6,14,16 |
| 供应商 | Tocris |
| 生物活性 | Potent antagonist for α7-containing neuronal nicotinic receptors (Ki = 1.4 nM). Interacts with α4β2 and α6β2 receptors at concentrations > 40 nM. Attenuates METH-induced neurotoxicity in mouse striatum in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 874.93 |
| 分子式 | C37H50N2O10.C6H8O7 |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 100 mM in DMSO |
| CAS号 | 21019-30-7 |
| 参考文献 | Escubedoet al (2005) Methyllycaconitine prevents methamphetamine-induced effects in mouse striatum: involvement of α7 nicotinic receptors. J.Pharmacol.Exp.Ther. 315 658. PMID: 16076935. Dobeliset al (1999) Effects of delphinium alkaloids on neuromuscular transmission. J.Pharmacol.Exp.Ther. 291 538. PMID: 10525069. Wardet al (1990) Methyllycaconitine: a selective probe for neuronal a-bungarotoxin binding sites. FEBS Lett. 270 45. PMID: 2226787. |