货号 | 5648/50 |
别名 | 2-[[4-[(7-Chloro-4-quinolinyl)amino |
供应商 | Tocris |
生物活性 | Autophagy inhibitor. Inhibits growth and induces apoptosis of renal cancer cells in vitro. Also inhibits TLR9. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >99 % |
计算分子量 | 433.95 |
分子式 | C18H28ClN3O5 |
可溶性/溶解性 | Soluble to 100 mM in water |
参考文献 | Leeet al (2015) Hydroxychloroquine Destabilizes Phospho-S6 in Human Renal Carcinoma Cells. PLoS ONE 10 e0131464. PMID: 26134285. Lamphieret al (2014) Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo. Mol.Pharmacol. 85 429. PMID: 24342772. |