| 货号 | 1657/50 |
| 别名 | (1R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,1 |
| 供应商 | Tocris |
| 生物活性 | Platelet-activating factor (PAF) receptor antagonist (Ki = 1.3 μM). Inhibits neutrophil degranulation and superoxide production in vitro and inhibits bronchoconstriction and is neuroprotective following oral administration in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 计算分子量 | 424.4 |
| 分子式 | C20H24O10 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 25 mM in ethanol |
| CAS号 | 15291-77-7 |
| 参考文献 | Maclennanet al (2002) The CNS effects of Ginkgo biloba extracts and ginkgolide B. Prog.Neurobiol. 67 235. PMID: 12169298. Foldes-Filepet al (1987) Inhibition by BN 52021 (ginkgolide B) of the binding of [3H]-platelet-activating factor to human neutrophil granulocytes. Biochem.Biophys.Res.Commun. 148 1412. PMID: 2825685. Desquandet al (1986) Interference of BN 52021 (ginkgolide B) with the bronchopulmonary effects of PAF-acether in the guinea-pig. Eur.J.Pharmacol. 127 83. PMID: 3019727. |