货号 | 1033/50 |
别名 | (E)-5-Methoxy-1-[4-(trifluoromethyl |
供应商 | Tocris |
生物活性 | Selective serotonin reuptake inhibitor; antidepressant. Binds to the human 5-HT transporter with a Ki of 1.6 nmol/l. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >99 % |
计算分子量 | 434.41 |
分子式 | C15H21F3N2O2.C4H4O4 |
可溶性/溶解性 | Soluble to 10 mM in water |
CAS号 | 61718-82-9 |
参考文献 | Owenset al (1997) Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J.Pharmacol.Exp.Ther. 283 1305. PMID: 9400006. Naritaet al (1996) Interactions of selective serotonin reuptake inhibitors with subtypes of σ receptors in rat brain. Eur.J.Pharmacol. 307 117. PMID: 8831113. Benfield and Ward (1986) Fluvoxamine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in depressive illness. Drugs 32 313. PMID: 3096686. Classenet al (1977) Fluvoxamine, a specific 5-hydroxytryptamine uptake inhibitor. Br.J.Pharmacol. 60 505. PMID: 302726. |