货号 | 1328/50 |
别名 | 8-Fluoro-5,6-dihydro-5-methyl-6-oxo |
供应商 | Tocris |
生物活性 | Benzodiazepine antagonist, non-selective for α1,α2,α3 or α5-containing GABAA receptors. Centrally active upon systemic administration in vivo. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >99 % |
计算分子量 | 303.29 |
分子式 | C15H14FN3O3 |
可溶性/溶解性 | Soluble to 25 mM in DMSO and to 5 mM in ethanol with gentle warming |
CAS号 | 78755-81-4 |
参考文献 | Atacket al (1999) Regional differences in the inhibition of mouse in vivo [3H]Ro 15-1788 binding reflect selectivity for α1 versus α2 and α3 subunit-containing GABAA receptors. Neuropsychopharmacology 20 255. PMID: 10063485. Dobl (1999) New insights into the mechanism of action of hypnotics. J.Psychopharmacol. 13 S11. PMID: 10667451. Polcet al (1981) Electrophysiological studies on the specific benzodiazepine antagonist Ro 15-1788. Naunyn Schmiedebergs Arch.Pharmacol. 316 317. PMID: 7196507. |