| 货号 | 3378/50 |
| 别名 | 3-Amino-N-(aminoiminomethyl)-6-chlo |
| 供应商 | Tocris |
| 生物活性 | TRPP3 channel inhibitor (IC50 = 10.5 μM). Inhibits the Na+/H+ exchanger (NHE). Derivative of amiloride (Cat. No. 0890). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 299.76 |
| 分子式 | C11H18ClN7O |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 50 mM in 1eq. HCl |
| 参考文献 | Horinouchiet al (2008) Functional role of Na+/H+ exchanger in Ca2+ influx mediated via human endothelin type A receptor stably expressed in Chinese hamster ovary cells. J.Pharm.Sci. 107 456. PMID: 18678984. Daiet al (2007) Inhibition of TRPP3 channel by amiloride and analogs. Mol.Pharmacol. 72 1576. PMID: 17804601. |