| 货号 | 0638/50 |
| 别名 | 7-Trifluoromethyl-4-(4-methyl-1-pip |
| 供应商 | Tocris |
| 生物活性 | 5-HT1B full agonist, 10-fold selective over 5-HT1A and 1000-fold selective over 5-HT2C receptors. Centrally active following systemic administration. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 566.49 |
| 分子式 | C17H17F3N4.2C4H4O4 |
| 可溶性/溶解性 | Soluble to 5 mM in water and to 40 mM in DMSO |
| CAS号 | 109028-10-6 |
| 参考文献 | Tomkins and O'Neill (2000) Effect of 5-HT1B receptor ligands on self-administration of ethanol in an operant procedure in rats. Pharmacol.Biochem.Behav. 66 129. PMID: 10837852. Schoeffter and Hoyer (1989) Interaction of arylpiperazines with 5-HT1A, 5-HT1B, 5-HT1C and 5-HT1D receptors: do discriminatory 5-HT1B receptor ligands exist? Naunyn Schmiedebergs Arch.Pharmacol. 339 675. PMID: 2770889. Nealeet al (1987) Biochemical and pharmacological characterization of CGS 12066B, a selective serotonin-1B agonist. Eur.J.Pharmacol. 136 1. PMID: 3496228. |