Azoramide (50 MG)
货号：
5796/50 基本售价：
5581.8 元 规格：
50 mg
产品信息
概述| 货号 | 5796/50 |
| 别名 | N-[2-[2-(4-Chlorophenyl)-4-thiazolyl]ethyl]butanamide |
性能| 供应商 | Tocris |
| 生物活性 | Modulator of unfolded protein response (UPR). Protects cells from ER stress by improving ER protein folding and activating ER chaperone capacity. Also improves ER calcium retention. Improves liver ER function, glucose homeostasis and glucose-stimulated insulin secretion in mouse obesity models. Orally bioavailable. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 308.83 |
| 分子式 | C15H17ClN2OS |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Fuet al (2015) Phenotypic assays identify azoramide as a small-molecule modulator of the unfolded protein response with antidiabetic activity. Sci.Transl.Med. 7 292ra98. PMID: 26084805. |
