| 货号 | 3698/50 |
| 别名 | 5,7-Dichloro-4-hydroxyquinoline-2-c |
| 供应商 | Tocris |
| 生物活性 | Sodium salt of 5,7-Dichlorokynurenic acid (Cat. No. 0286), a potent antagonist at the glycine site of the NMDA receptor (Ki = 79 nM vs. [3H]-glycine). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 280.04 |
| 分子式 | C10H4Cl2NNaO3 |
| 可溶性/溶解性 | Soluble to 100 mM in 1eq. NaOH |
| 参考文献 | Baronet al (1990) Activity of 5,7-dichlorokynurenic acid. A potent antagonist at the NMDA receptor-associated glycine binding site. Mol.Pharmacol. 38 554. PMID: 2172769. Mooreet al (1990) Substituted kynurenic acid derivatives. Potent and selective antagonists at the glycine site on the NMDA receptor. Eur.Fed.Med.Chem. (under auspices of IUPAC) XIth I. |