Nosiheptide
货号：
17094-5mg 基本售价：
5544.0 元 规格：
5 mg
产品信息
概述| 货号 | 17094-5mg |
| 描述 | Nosiheptide is a thiopeptide antibiotic that inhibits bacterial protein synthesis by interfering with the function of elongation factors.1,2 It is effective against many different methicillin-resistant S. aureus strains (MICs ≤ 0.25 mg/L), Enterococcus spp (MICs ≤ 0.125 mg/L), and the BI strain of C. difficile (MIC = 0.008 mg/L) but inactive against most Gram-negative bacteria.3 |
| 别名 | Multhiomycin;NSC 307240;RP 9671; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Cundliffe, E., and Thompson, J. The mode of action of nosiheptide (multhiomycin) and the mechanism of resistance in the producing organism. J.Gen.Microbiol. 126(1), 185-192 (1981).
2.Yu, Y.,Duan, L.,Zhang, Q., et al. Nosiheptide biosynthesis featuring a unique indole side ring formation on the characteristic thiopeptide framework. ACS Chemical Biology 4(10), 855-864 (2009).
3.Haste, N.M.,Thienphrapa, W.,Tran, D.N., et al. Activity of the thiopeptide antibiotic nosiheptide against contemporary strains of methicillin-resistant Staphylococcus aureus. J.Antibiot.(Tokyo) 65(12), 593-598 (2012).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 1222.4 |
| 分子式 | C51H43N13O12S6 |
| CAS号 | 56377-79-8 |
| 稳定性 | ≥ 2 years |
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