货号 | 3586/50 |
别名 | 3-[2-(Dimethylamino)ethyl]-N-methyl |
供应商 | Tocris |
生物活性 | 5-HT1 receptor agonist (Ki values are 17, 27 and 100 nM at 5-HT1D, 5-HT1B and 5-HT1A receptors respectively). Antimigraine agent. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >99 % |
计算分子量 | 413.49 |
分子式 | C14H21N3O2S.C4H6O4 |
可溶性/溶解性 | Soluble to 100 mM in water and to 75 mM in DMSO |
CAS号 | 103628-48-4 |
参考文献 | Ottaniet al (2004) Effect of sumatriptan in different models of pain in rats. Eur.J.Pharmacol. 497 181. PMID: 15306203. Peroutka (1990) Sumatriptan in acute migraine: pharmacology and review of world experience. Headache 30 554. PMID: 2177047. Peroutka and McCarthy (1989) Sumatriptan (GR 43175) interacts selectivity with 5-HT1B and 5-HT1D binding sites. Eur.J.Pharmacol. 163 133. PMID: 2545459. |