| 货号 | 1265/10 |
| 别名 | D-4-[(2E)-3-Phosphono-2-propenyl]-2 |
| 供应商 | Tocris |
| 生物活性 | Potent and competitive NMDA antagonist (Ki = 40 nM). Centrally active following systemic administration. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 250.19 |
| 分子式 | C8H15N2O5P |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 117414-74-1 |
| 参考文献 | Potschkaet al (1999) Effects of the NMDA receptor antagonist D-CPPene on extracellular levels of dopamine and dopamine and serotonin metabolites in striatum of kindled and non-kindled rats. Eur.J.Pharmacol. 374 175. PMID: 10422758. Loweet al (1990) D-CPP-ene (SDZ EAA 494), a potent and competitive N-methyl-D-aspartate (NMDA) antagonist: effect on spontaneous activity and NMDA-induced depolarizations in the rat neocortical slice preparation, compared with other CPP derivatives and MK-801. Neurosci.Lett. 113 315. PMID: 2166255. Aebischeret al (1989) Synthesis and NMDA antagonistic properties of the enantiomers of 4-(3-phosphonopropyl)piperazine-2-carboxylic acid (CPP) and of the unsaturated analogue (E)-4-(3-phosphono-2-enyl)piperazine-2-carboxylic acid (CPP-ene). Helv.Chim.Acta 721043. |