Thiodiglycolic Acid-d4
货号：
9002478-5mg 基本售价：
5488.0 元 规格：
5 mg
产品信息
概述| 货号 | 9002478-5mg |
| 描述 | Thiodiglycolic acid-d4(TDGA-d4) contains four deuterium atoms at the 2, 2, 2’, and 2’ positions. It is intended for use as an internal standard for the quantification of TDGA by GC- or LC-mass spectrometry. TDGA is a product of interaction of the cysteine component of glutathione with two-carbon units released during catabolism. It is found in concentrations below 20 mg/l in urine of healthy individuals and elevated following ingestion of certain drugs.1 Determination of TDGA concentration in urine has been used to characterize the metabolism of substances participating in methionine synthesis in order to identify imbalances leading to hyperhomocystinuria.2 Additionally, because TDGA is used as raw material in the polymer industry, its detection in human urine has served as a biomarker for exposure to carcinogenic vapors such as vinylchloride monomer produced during polymer manufacture.2 |
| 别名 | Dicarboxydimethyl sulfide-d4;Mercaptodiacetic Acid-d4;TDGA-d4;Thiodiacetic Acid-d4; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Navratil, T.,Petr, M.,Senholdova, Z., et al. Diagnostic significance of urinary thiodiglycolic acid as a possible tool for studying the role of vitamins B12 and folates in the metabolism of thiolic substances. Physiol.Res. 56(1), 113-122 (2007).
2.Cheng, Y.J.,Huang, Y.F., and Ma, Y.C. Urinary thiodiglycolic acid levels for vinyl chloride monomer-exposed polyvinyl chloride workers. J.Occup.Environ.Med. 43(11), 934-938 (2001).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥99% deuterated forms (d1-d4) |
| 计算分子量 | 154.2 |
| 分子式 | C4H2D4O4S |
| CAS号 | 132090-51-8 |
| 稳定性 | ≥ 2 years |
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