| 货号 | 17572-5g |
| 描述 | Guanidinoethyl sulfonate, also known as taurocyamine, is a natural guanidine-taurine analog derived from taurine. It is an intermediate of taurine and hypotaurine metabolism and is phosphorylated by taurocyamine kinase.1 Guanidinoethyl sulfonate competitively inhibits taurine uptake by sodium-dependent taurine transporters in rat hepatocytes (Ki = 1.75 mM).2 It also acts as a competitive glycine receptor antagonist in mouse striatal neurons.3 Plasma levels of guanidinoethyl sulfonate are significantly increased in patients with chronic renal failure.4 |
| 别名 | NSC 667063;Taurocyamine; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Uda, K.,Saishoji, N.,Ichinari, S., et al. Origin and properties of cytoplasmic and mitochondrial isoforms of taurocyamine kinase. FEBS Journal 272, 3521-3530 (2005). 2.Ohkuma, S.,Tamura, J.i.,Kuriyama, K., et al. Characteristics of taurine transport in freshly isolated rat hepatocytes. Japan.J.Pharmacol. 31, 1061-1070 (1981). 3.Sergeeva, O.A.,Chepkova, A.N., and Hass, H.L. Guanidinoethyl sulphonate is a glycine receptor antagonist in striatum. British Journal of Pharmacology 137, 855-860 (2002). 4.Tanaka, A.,Takahashi, Y.,Mizokuchi, M., et al. Plasma, urinary, and erythrocyte concentrations of guanidino compounds in patients with chronic renal failure. Ren Fail. 21(5), 499-514 (1999). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 167.2 |
| 分子式 | C3H9N3O3S |
| CAS号 | 543-18-0 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |