EGFR/ErbB2 Inhibitor
货号：
17568-5mg 基本售价：
5488.0 元 规格：
5 mg
产品信息
概述| 货号 | 17568-5mg |
| 描述 | EGFR/ErbB2 inhibitor is a cell-permeable inhibitor of EGFR and c-ErbB2 (HER2, Neu; IC50s = 20 and 79 nM, respectively).1 It inhibits the proliferation of cancer cells overexpressing either c-ErbB2 or EGFR (IC50s = 2.3-2.5 µM).1 EGFR/ErbB2 inhibitor displays a high level of selectivity for these kinases.2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Cockerill, S.,Stubberfield, C.,Stables, J., et al. Indazolylamino quinazolines and pyridopyrimidines as inhibitors of the EGFr and C-erbB-2. Bioorganic & Medicinal Chemistry Letters 11, 1401-1405 (2001).
2.Anastassiadis, T.,Deacon, S.W.,Devarajan, K., et al. Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity. Nat.Biotechnol. 29(11), 1039-1045 (2011).
|
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 387.4 |
| 分子式 | C23H21N3O3 |
| CAS号 | 179248-61-4 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
