15-keto Fluprostenol
货号：
16785-10mg 基本售价：
5488.0 元 规格：
10 mg
产品信息
概述| 货号 | 16785-10mg |
| 描述 | Fluprostenol is an F-series prostaglandin analog which has been approved for many years as a luteolytic in veterinary animals.1 The isopropyl ester of fluprostenol (travoprost) was recently introduced as an ocular hypotensive drug.2 Oxidation of the C-15 hydroxyl group of fluprostenol produces 15-keto fluprostenol. 15-keto Fluprostenol is a potential metabolite of fluprostenol when administered to animals. 15-keto Fluprostenol is also one of the common minor impurities found in commercial preparations of the bulk drug compound. Products of β-oxidation account for most of the metabolites of fluprostenol recovered in plasma and urine. However, 15-keto fluprostenol is a minor metabolite, and one which could be enhanced in situations where β-oxidation is reduced. |
性能| 供应商 | Cayman |
| 应用文献 |
1.Dukes, M.,Russell, W., and Walpole, A.L. Potent luteolytic agents related to prostaglandin F2α. Nature 250, 330-331 (1974).
2.Sorbera, L.A., and Castañer, J. Travoprost. Drugs of the Future 25, 41-45 (2000).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 456.5 |
| 分子式 | C23H27F3O6 |
| 稳定性 | ≥ 1 year |
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