MN-001
货号：
11948-5mg 基本售价：
5488.0 元 规格：
5 mg
产品信息
概述| 货号 | 11948-5mg |
| 描述 | MN-001 is an orally bioavailable anti-inflammatory agent whose mechanisms of action include inhibition of eosinophil migration, antagonism of leukotriene receptors, and inhibition of phosphodiesterases 3 and 4.1 Other mechanisms of action described for MN-001 include the inhibition of 5-lipoxygenase, phospholipase C, and thromboxane A2.1 MN-001 is reported to produce antifibrotic and anti-inflammatory activity in multiple preclinical models and is undergoing clinical investigations for use in the treatment of patients with either idiopathic pulmonary fibrosis or non-alcoholic steatohepatitis.1,2 |
| 别名 | KCA 757;Tipelukast; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Rajasekaran, M.,Locke, K.W., and Parsons, C.L. MN-001, a novel oral anti-inflammatory agent, suppresses bladder hyperactivity in a rat model. BJU Int. 98(2), 430-434 (2006).
2.. MN 001: KCA 757, KCA-757, MN-001. Drugs R.D. 8(6), 400-402 (2007).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 530.7 |
| 分子式 | C29H38O7S |
| CAS号 | 125961-82-2 |
| 稳定性 | ≥ 2 years |
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