| 货号 | 15934-10mg |
| 描述 | Syntide-2 is a synthetic peptide recognized as a substrate by Ca2+/calmodulin-dependent protein kinase II (CaMKII; Km = 12 µM).1 Its sequence is derived from the phosphorylation site 2 on glycogen synthase, a target of CaMKII action.1 This peptide has been used as a probe to assay CaMKII activity; however, protein kinase C, CaMKV, Raf-1, and other kinases are also known to recognize syntide-2 as a substrate.1,2,3,4 |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Hashimoto, Y. and Soderling, T.R. Calcium calmodulin-dependent protein kinase II and calcium phospholipid-dependent protein kinase activities in rat tissues assayed with a synthetic peptide. Archives of Biochemistry and Biophysics 252(2), 418-425 (1987). 2.Inoue, S.,Mizutani, A.,Sugita, R., et al. Purification and characterization of a novel protein activator of Ca2+/calmodulin-dependent protein kinase I. Biochemical and Biophysical Research Communications 215(3), 861-867 (1995). 3.Kumar, K.A. and Babu, P.P. CaM kinase II-alpha activity, levels and Ca/calmodulin dependent phosphorylation of substrate proteins in mice brain during fatal murine cerebral malaria. Neuroscience Letters 336, 121-125 (2003). 4.Force, T.,Bonventre, J.V.,Heidecker, G., et al. Enzymatic characteristics of the c-Raf-1 protein kinase. Proceedings of the National Academy of Sciences of the United States of America 91, 1270-1274 (1994). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 计算分子量 | 1507.8 |
| 分子式 | C68H122N20O18 |
| CAS号 | 108334-68-5 |
| 稳定性 | ≥ 2 years |
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