PD 174265
货号：
17649-5mg 基本售价：
5390.0 元 规格：
5 mg
产品信息
概述| 货号 | 17649-5mg |
| 描述 | PD 174265 is a potent, cell-permeable inhibitor of the tyrosine kinase activity of the epidermal growth factor (EGF) receptor (IC50 = 0.45 nM).1 It is effective in cells, blocking tyrosine phosphorylation induced by either EGF or heregulin (IC50s = 39 and 220 nM, respectively).1 The action of PD 174265 is reversible, which makes it a useful tool for comparative studies with irreversible inhibitors of EGFR kinase activity.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Fry, D.W.,Bridges, A.J.,Denny, W.A., et al. Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor. Proceedings of the National Academy of Sciences of the United States of America 95, 12022-12027 (1998).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 371.2 |
| 分子式 | C17H15BrN4O |
| CAS号 | 216163-53-0 |
| 稳定性 | ≥ 2 years |
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