Rubratoxin A
货号：
19605-500ug 基本售价：
5362.0 元 规格：
500 ug
产品信息
概述| 货号 | 19605-500ug |
| 描述 | Rubratoxin A is a natural mycotoxin and competitive inhibitor of protein phosphatase 2A (PP2A; IC50 = 170 nM).1 It has no significant effect on several other phosphatases, including PP1, PP2B, and protein tyrosine phosphatase 1B. Rubratoxin A drives overphosphorylation of PP2A substrate proteins in cultured cells treated for three hours at 20 µM.1 It causes suppression of tumor metastasis and reduction of primary tumor volume in mouse xenografts.1 |
| 别名 | BRN 1633008;HSDB 3532; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Wada, S.i.,Usami, I.,Umezawa, Y., et al. Rubratoxin A specifically and potently inhibits protein phosphatase 2A and suppresses cancer metastasis. Cancer Science 101(3), 743-750 (2010).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 520.5 |
| 分子式 | C26H32O11 |
| CAS号 | 22467-31-8 |
| 稳定性 | ≥ 3 years |
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