(±)-Cromakalim
货号：
14601-50mg 基本售价：
5362.0 元 规格：
50 mg
产品信息
概述| 货号 | 14601-50mg |
| 描述 | (±)-Cromakalim is a prototypical activator of the ATP-sensitive potassium channel, SUR2-Kir6, that displays anti-ischemic (EC25 = 8.9 μM) and cardioprotective (IC50 = 0.03 μM) effects in rat hearts.1 (±)-Cromakalim has also been shown to relax bladder smooth muscle in vitro.1 It has been used to investigate potassium channel biology and as a scaffold to develop increasingly selective K+ channel openers with clinical relevance.1 |
| 别名 | BRL 34915; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Coghlan, M.J.,Carroll, W.A. and Gopalakrishnan, M. Recent developments in the biology and medicinal chemistry of potassium channel modulators: Update from a decade of progress. Journal of Medicinal Chemistry 44(11), 1627-1653 (2001).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | 4 |
| 纯度 | ≥99% |
| 计算分子量 | 286.3 |
| 分子式 | C16H18N2O3 |
| CAS号 | 94470-67-4 |
| 稳定性 | ≥ 6 months |
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