6877002 (50 MG)
货号：
5602/50 基本售价：
5343.9 元 规格：
50 mg
产品信息
概述| 货号 | 5602/50 |
| 别名 | 3-[(2,5-Dimethylphenyl)amino]-1-phenyl-2-propen-1-one |
性能| 供应商 | Tocris |
| 生物活性 | CD40-TRAF6 interaction inhibitor. Suppresses CD40-induced IL-1β and IL-6 expression in macrophages in vitro. Improves insulin sensitivity, reduces adipose tissue inflammation, and ameliorates hepatosteatosis in diet-induced obese mice. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 251.32 |
| 分子式 | C17H17NO |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Chatzigeorgiouet al (2014) Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance. Proc.Natl.Acad.Sci.U.S.A. 111 2686. PMID: 24492375. |
