IC261
货号:
9669-25 基本售价:
5342.5 元 规格:
25mg
产品信息
概述货号 | 9669-25 |
描述 | IC261 is a reversible, ATP-competitive inhibitor of casein kinase 1 (CK1) (IC₅₀ = ~1 µM for CK1δ and CK1ɛ and 16 µM for CK1α). It is at least 100-fold less effective against PKA, p34cdc2, and p55fyn. IC261, at 1 µM, inhibits cytokinesis in primary mouse embryo fibroblasts. IC261 induces cell cycle arrest and apoptosis of human cancer cells via CK1δ/ɛ and Wnt/β-catenin independent inhibition of mitotic spindle formation. |
性能供应商 | Biovision |
运输条件 | Blue Ice |
存放说明 | -20℃ |
外观 | Yellow solid |