| 货号 | 21602-1mg |
| 描述 | PBFI AM is a cell-permeable, potassium-sensitive fluorophore used to measure potassium changes in cells and intracellular compartments.1,2 As PBFI AM enters cells, it is hydrolyzed by intracellular esterases to produce PBFI. The affinity of PBFI for potassium is sodium-dependent (Kd = 44 and 5.1 mM with or without sodium, respectively).3 Absorption and emission maxima are 336 and 480-557 nm, respectively.4,5 |
| 别名 | Potassium-binding Benzofuran Isophthalate Acetoxymethyl ester; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Grieshaber, S.,Swanson, J.A. and Hackstadt, T. Determination of the physical environment within the Chlamydia trachomatis inclusion using ion-selective ratiometric probes. Cell. Microbiol. 4(5), 273-283 (2002). 2.Ljubkovic, M.,Marinovic, J.,Fuchs, A., et al. Targeted expression of Kir6.2 in mitochondria confers protection against hypoxic stress. J. Physiol. 577(Pt 1), 17-29 (2006). 3.Halperin, S.J. and Lynch, J.P. Effects of salinity on cytosolic Na+ and K+ in root hairs of Arabidopsis thaliana: In vivo measurements using the fluorescent dyes SBFI and PBFI. J. Exp. Bot. 54(390), 2035-2043 (2003). 4.Sabnis, R.W. Handbook of biological dyes and stains: Synthesis and industrial applications. (2010). 5.Jezek, P.,Mahdi, F. and Garlid, K.D. Reconstitution of the beef heart and rat liver mitochondrial K+/H+(Na+/H+) antiporter. Quantitation of K+ transport with the novel fluorescent probe, PBFI. J. Biol. Chem. 265(18), 10522-10526 (1990). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 1171.1 |
| 分子式 | C58H62N2O24 |
| CAS号 | 124549-23-1 |
| 稳定性 | ≥ 1 year |
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