COX-2 (ovine) Inhibitor Screening Assay Kit
货号:
702000-96Well 基本售价:
5250.0 元 规格:
96 wells
产品信息
概述货号 | 702000-96Well |
描述 | COX-1 and COX-2 catalyze the production of the prostaglandin (PG), thromboxane, and prostacyclin precursor PGH2. COX-2 is responsible for the biosynthesis of PGs under acute inflammatory conditions. This inducible COX-2 is believed to be the target enzyme for the anti-inflammatory activity of nonsteroidal anti-inflammatory drugs. The COX-2 (ovine) Inhibitor Screening Assay directly measures PGF2α (Item No. 16010) by SnCl2 reduction of COX-2-derived PGH2 (Item No. 17020) produced in the COX-2 reaction. The prostanoid product is quantified via enzyme immunoassay (EIA) using a broadly specific antiserum that binds to all the major PG compounds. This assay includes ovine COX-2 allowing the user to screen specific inhibitors. This assay is an excellent tool that can be used for general inhibitor screening, or to eliminate false positive leads generated by less specific methods. |
性能供应商 | Cayman |
运输条件 | Dry ice in continental US; may vary elsewhere |
存放说明 | -80 |
稳定性 | ≥ 1 year |
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