Dinophysistoxin-1
货号：
10011497-100ug 基本售价：
5250.0 元 规格：
100 ug
产品信息
概述| 货号 | 10011497-100ug |
| 描述 | Dinophysistoxin-1 is a marine toxin produced by dinoflagellates that is known to accumulate in shellfish and cause diarrheic shellfish poisoning.1 It inhibits serine/threonine protein phosphatases 1 (PP1) and PP2A (IC50 = 0.104 nM) and has been shown to promote cancer cell growth in tumor cell lines and animal models.2,3 |
| 别名 | DTX1;3-methyl Okadaic Acid; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Fernández, D.A.,Louzao, M.C.,Fraga, M., et al. Experimental basis for the high oral toxicity of dinophysistoxin 1: A comparative study of DSP. Toxins (Basel) 6(1), 211-228 (2014).
2.Ikehara, T.,Imamura, S.,Yoshina, A., et al. PP2A inhibition assay using recombinant enzyme for rapid detection of okadaic acid and its analogs in shellfish. Toxins (Basel) 2(1), 195-204 (2010).
3.Fujiki, H.,Suganuma, M.,Yoshizawa, S., et al. Mechanisms of action of okadaic acid class tumor promoters on mouse skin. Environ. Health Perspect. 93, 211-214 (1991).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 819 |
| 分子式 | C45H70O13 |
| CAS号 | 81720-10-7 |
| 稳定性 | ≥ 2 years |
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