MG-132
货号:
1703-25 基本售价:
5221.5 元 规格:
25mg
产品信息
概述货号 | 1703-25 |
描述 | A cell-permeable, potent, and reversible proteasome inhibitor (Ki = 4 nM). Reduces degradation of ubiquitin-conjugated proteins in mammalian cells and permeable strains of yeast by the 26S complex without affecting its ATPase or isopeptidase activities. Activates c-Jun N-terminal kinase (JNK1), which initiates apoptosis. Inhibits NF-kB activation (IC₅₀ = 3 µM). Prevents γ-secretase cleavage. |
性能供应商 | Biovision |
运输条件 | Blue Ice |
存放说明 | -20℃ |
外观 | White to off-white solid |