| 货号 | 1668/1 |
| 供应商 | Tocris |
| 生物活性 | Potent and selective tachykinin NK2 receptor agonist (EC50 = 3.7 nM in rat colon). Displays > 1000- and > 300-fold selectivity over NK1 and NK3 receptors respectively. Active in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 921.12 |
| 分子式 | C42H68N10O11S |
| 可溶性/溶解性 | Soluble to 1 mg/ml in 20% ethanol / water |
| CAS号 | 137593-52-3 |
| 序列号 | KDSFVGLM (Modifications: Leu-7 = R-γ-lactam-Leu, Met-8 = C-terminal amide) |
| 参考文献 | Changet al (2000) Tachykinin receptor subtypes in the isolated guinea pig heart and their role in mediating responses to neurokinin A. J.Pharmacol.Exp.Ther. 294 147. PMID: 10871306. Chizhet al (1995) Endogenous modulation of excitatory amino acid responsiveness by tachykinin NK1 and NK2 receptors in the rat spinal cord. Br.J.Pharmacol. 115 1013. PMID: 7582497. Dealet al (1992) Conformationally constrained tachykinin analogues: potent and highly selective neurokinin NK-2 receptor agonists. J.Med.Chem. 35 4195. PMID: 1331460. |