| 货号 | 0868/50 |
| 别名 | N-Acetyl-L-tryptophan 3,5-bis(trifluoromethyl)benzyl ester |
| 供应商 | Tocris |
| 生物活性 | Potent and highly selective competitive tachykinin NK1 receptor antagonist (IC50 = 2.3 nM). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 472.39 |
| 分子式 | C20H18F6N2O3 |
| 可溶性/溶解性 | Soluble to 100 mM in ethanol and to 100 mM in DMSO |
| CAS号 | 148451-96-1 |
| 参考文献 | Kuoet al (1998) Lipopolysaccharide enhances neurogenic plasma exudation in guinea-pig airways. Br.J.Pharmacol. 125 711. PMID: 9831906. Cascieriet al (1994) Characterization of the interaction of N-acyl-L-tryptophan benzyl ester neurokinin antagonists with the human neurokinin-1 receptor. J.Biol.Chem. 269 6587. PMID: 7509807. MacLeodet al (1994) Identification of L-tryptophan derivatives with potent and selective antagonist activity at the NK1 receptor. J.Med.Chem. 37 1269. PMID: 7513763. MacLeodet al (1993) N-Acyl-L-tryptophan benzyl esters: potent substance P receptor antagonists. J.Med.Chem. 36 2044. PMID: 8393115. |