| 货号 | 0545/50 |
| 别名 | (1R*,2S*)-erythro-2-(4-Benzylpiperi |
| 供应商 | Tocris |
| 生物活性 | NMDA receptor antagonist, acting at the polyamine site. Also an α-adrenergic vasodilator. σ2 ligand displaying about 3-fold selectivity over σ1sites. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 400.49 |
| 分子式 | C21H27NO2.紺4H6O6 |
| 可溶性/溶解性 | Soluble to 15 mM in water with gentle warming |
| CAS号 | 23210-56-2 |
| 参考文献 | Shalabyet al (1992) Neuroprotective effects of the N-methyl-D-aspartate receptor antagonists ifenprodil and SL-82,0715 on hippocampal cells in culture. J.Pharmacol.Exp.Ther. 260 925. PMID: 1346650. Schoemakeret al (1990) Polyamine-sensitive binding of [3H]ifenprodil, a novel NMDA antagonist to the rat cerebral cortex. Eur.J.Pharmacol. 176 249. PMID: 2178949. Reynolds and Miller (1989) Ifenprodil is a novel type of N-methyl-D-aspartate receptor antagonist: interaction with polyamines. Mol.Pharmacol. 36 758. PMID: 2555674. Gottiet al (1988) Ifenprodil and SL-82,0715 as cerebral anti-ischemic agents. 1. Evidence for efficacy in models of focal cerebral ischemia. J.Pharmacol.Exp.Ther. 247 1211. PMID: 2849668. |