| 货号 | 2425/500U |
| 供应商 | Tocris |
| 生物活性 | Rat form of the predominant amyloid β-peptide found in plaques associated with Alzheimer's disease. Leads to a large shift in the bax/bcl-2 ratio in favour of pro-apoptotic bax. Neurotoxic. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 4417.99 |
| 分子式 | C199H307N53O |
| 可溶性/溶解性 | Soluble to 1 mg/ml in 0.1% Ammonia |
| 序列号 | DAEFGHDSGFEVRHQKLVFFAEDVGSNKGA |
| 参考文献 | Clementiet al (2006) Alzheimer's amyloid β-peptide (1-42) induces cell death in human neuroblastoma via bax/bcl-2 ratio increase: An intriguing role for methionine 35. Biochem.Biophys.Res.Comm. 342206. Van Nostrandet al (1996) Amyloid β-protein induces the cerebrovascular cellular pathology of Alzheimer's disease and related disorders. Ann.N.Y.Acad.Sci. 777 297. PMID: 8624102. Glenner and Wong (1984) Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem.Biophys.Res.Comm. 120885. |