| 货号 | 0286/50 |
| 别名 | 5,7-Dichloro-4-hydroxyquinoline-2-c |
| 供应商 | Tocris |
| 生物活性 | Potent antagonist at the glycine site of the NMDA receptor (Ki = 79 nM vs. [3H]-glycine). Sodium salt (Cat. No. 3698) also available. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 258.06 |
| 分子式 | C10H5CI2NO3 |
| 可溶性/溶解性 | Soluble to 100 mM in 1eq. NaOH and to 100 mM in DMSO |
| CAS号 | 131123-76-7 |
| 参考文献 | Baronet al (1990) Activity of 5,7-dichlorokynurenic acid. A potent antagonist at the NMDA receptor-associated glycine binding site. Mol.Pharmacol. 38 554. PMID: 2172769. Mooreet al (1990) Substituted kynurenic acid derivatives. Potent and selective antagonists at the glycine site on the NMDA receptor. Eur.Fed.Med.Chem. (under auspices of IUPAC) XIth I 29. |