LY2874455
货号：
20843-25mg 基本售价：
5040.0 元 规格：
25 mg
产品信息
概述| 货号 | 20843-25mg |
| 描述 | LY2874455 is a pan-inhibitor of fibroblast growth factor receptor (FGFR) tyrosine kinases with IC50 values of 2.8, 2.6, 6.4, 6, and 7 nM for FGFR1, FGFR2, FGFR3, FGFR4, and VEGFR2, respectively.1 It has been shown to inhibit proliferation of KMS-11, OPM-2, SNU-16, and KATO-III cancer cells in vitro and in tumor xenografts in mice.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Zhao, G.,Li, W.-y.,Chen, D., et al. A novel, selective inhibitor of fibroblast growth factor receptors that shows a potent broad spectrum of antitumor activity in several tumor xenograft models. Mol. Cancer Ther. 10(11), 2200-2210 (2011).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 444.3 |
| 分子式 | C21H19Cl2N5O2 |
| CAS号 | 1254473-64-7 |
| 稳定性 | ≥ 2 years |
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