| 货号 | 3379/50 |
| 别名 | 3,5-Diamino-6-chloro-N-[imino(pheny |
| 供应商 | Tocris |
| 生物活性 | TRPP3 channel inhibitor (IC50 = 0.14 μM). Also inhibits epithelial Na+ channels (Kd = 0.4 nM for a high affinity site on the epithelial Na+ channel). Derivative of amiloride (Cat. No. 0890). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 401.83 |
| 分子式 | C12H12ClN7O.CH |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Daiet al (2007) Inhibition of TRPP3 channel by amiloride and analogs. Mol.Pharmacol. 72 1576. PMID: 17804601. Barbryet al (1989) Biochemical identification of two types of phenamil binding sites associated with amiloride-sensitive Na+ channels. Biochemistry. 28 3744. PMID: 2546581. |