| 货号 | 5028/50 |
| 别名 | N-(4-Methyl-2-quinazolinyl)-guanidi |
| 供应商 | Tocris |
| 生物活性 | Selective opener of acid-sensing ion channel 3 (ASIC3) at pH 7.4. Alters the pH dependence of ASIC1a and ASIC1b; does not affect the activation curve of ASIC2a. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 237.69 |
| 分子式 | C10H11N5.HCl |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO and to 5 mM in water with gentle warming |
| 参考文献 | Alijevic and Kellenberger (2012) Subtype-specific modulation of acid-sensing ion channel (ASIC) function by 2-guanidine-4-methylquinazoline. J.Biol.Chem. 287 36059. PMID: 22948146. Liet al (2010) ASIC3 channels integrate agmatine and multiple inflammatory signals through the nonproton ligand sensing domain. Mol.Pain 6 88. PMID: 21143836. |