| 货号 | 5375/50 |
| 别名 | 2-(3,4-Dihydroxyphenyl)-2-oxoethyl ester thiocyanic acid |
| 供应商 | Tocris |
| 生物活性 | BiP (Hsp70-5) ER chaperone inducer; induces BiP expression in vitroandin vivo. Protects against ER-stress induced cell death in neuronal and retinal cell lines. Also protects against ischaemia-induced hippocampal cell death in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 209.22 |
| 分子式 | C9H7NO3S |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| 参考文献 | Inokuchiet al (2009) Effect of an inducer of BiP, a molecular chaperone, on endoplasmic reticulum (ER) stress-induced retinal cell death. Invest.Ophthalmol.Vis.Sci. 50 334. PMID: 18757512. Kudoet al (2008) A molecular chaperone inducer protects neurons from ER stress. Cell Death Differ. 15 364. PMID: 18049481. Oidaet al (2008) Induction of BiP, an ER-resident protein, prevents the neuronal death induced by transient forebrain ischemia in gerbil. Brain Res. 1208 217. PMID: 18395193. |