RO4929097
货号:
2011-5 基本售价:
4979.5 元 规格:
5mg
产品信息
概述货号 | 2011-5 |
描述 | RO4929097 is a small molecule γ-secretase inhibitor (IC₅₀ = 4 nM). It binds to γ-secretase and blocks the activation of Notch receptors, which may inhibit tumor cell proliferation. RO4929097 inhibits Notch processing in tumor cells as measured by the reduction of intracellular Notch expression by Western blot. RO4929097 produces a less transformed and flattened slower-growing phenotype but does not induce apoptosis or block tumor cell proliferation. |
性能供应商 | Biovision |
运输条件 | Blue Ice |
存放说明 | -20℃ |
外观 | Off-white solid |