| 货号 | 1764/1 |
| 供应商 | Tocris |
| 生物活性 | Bioactive endogenous peptide substrate for endopeptidase 24.15 (ep24.15), neurolysin (ep24.16) and ACE. Ki values are 27.76, 3.43 and 1.87 μM respectively. Potent hypotensive in vivo. Also acts as a selective CB1 receptor inverse agonist. Displays antinociceptive activity and induces hypophagia in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1088.27 |
| 分子式 | C53H77N13O12 |
| 可溶性/溶解性 | Soluble to 2 mg/ml in 20% acetonitrile |
| CAS号 | 568588-77-2 |
| 序列号 | PVNFKFLSH |
| 参考文献 | Toddet al (2010) The peptide hemopressin acts through CB1 cannabinoid receptors to reduce food intake in rats and mice. J.Neurosci. 30 7369. PMID: 20505104. Heimannet al (2007) Hemopressin is an inverse agonist of CB1 cannabinoid receptors. Proc.Natl.Acad.Sci.U.S.A. 104 20588. PMID: 18077343. Rioliet al (2003) Novel natural peptide substrates for endopeptidase 24.15, neurolysin, and angiotensin-converting enzyme. J.Biol.Chem. 278 8547. PMID: 12500972. |